Tuesday 6 September 2016

Penicillin G Benzathine Suspension



Pronunciation: PEN-i-SIL-in G BEN-za-theen
Generic Name: Penicillin G Benzathine
Brand Name: Bicillin L-A

Do not inject Penicillin G Benzathine Suspension in or near an artery or vein. It should only be injected into muscle. There have been reports of serious side effects, including death, when Penicillin G Benzathine Suspension has been injected into a vein.





Penicillin G Benzathine Suspension is used for:

Treating some types of infections caused by certain bacteria.


Penicillin G Benzathine Suspension is a penicillin antibiotic. It works by interfering with the formation of the bacteria's cell wall while it is growing. This weakens the cell wall and kills the bacteria.


Do NOT use Penicillin G Benzathine Suspension if:


  • you are allergic to any ingredient in Penicillin G Benzathine Suspension or to other penicillins

  • you are taking a tetracycline antibiotic

Contact your doctor or health care provider right away if any of these apply to you.



Before using Penicillin G Benzathine Suspension:


Some medical conditions may interact with Penicillin G Benzathine Suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have diarrhea or a stomach infection, especially in children 9 years old or younger

  • if you have diabetes

Some MEDICINES MAY INTERACT with Penicillin G Benzathine Suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Probenecid because it may be increase the risk of Penicillin G Benzathine Suspension's side effects

  • Chloramphenicol or tetracyclines because they may decrease Penicillin G Benzathine Suspension's effectiveness

  • Anticoagulants (eg, warfarin) or methotrexate because their actions and the risk of their side effects may be increased by Penicillin G Benzathine Suspension

  • Anticoagulants (eg, warfarin), chloramphenicol, or oral contraceptives (birth control pills) because their effectiveness may be decreased by Penicillin G Benzathine Suspension

This may not be a complete list of all interactions that may occur. Ask your health care provider if Penicillin G Benzathine Suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Penicillin G Benzathine Suspension:


Use Penicillin G Benzathine Suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Penicillin G Benzathine Suspension is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Penicillin G Benzathine Suspension at home, a health care provider will teach you how to use it. Be sure you understand how to use Penicillin G Benzathine Suspension. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Penicillin G Benzathine Suspension works best if it is given at the same time each day.

  • Shake well before each use. Store Penicillin G Benzathine Suspension in the refrigerator. Do not freeze.

  • Penicillin G Benzathine Suspension should not be injected into or near an artery or vein. Penicillin G Benzathine Suspension should be injected into muscle, preferably in the upper outer portion of the buttocks. In children, Penicillin G Benzathine Suspension should be injected into the thigh.

  • To clear up your infection completely, use Penicillin G Benzathine Suspension for the full course of treatment. Keep using it even if you feel better in a few days.

  • If you miss a dose of Penicillin G Benzathine Suspension, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Penicillin G Benzathine Suspension.



Important safety information:


  • Penicillin G Benzathine Suspension may cause dizziness, drowsiness, or blurred vision. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not take Penicillin G Benzathine Suspension if you have had a severe allergic reaction to a penicillin antibiotic (eg, amoxicillin, ampicillin) or a cephalosporin antibiotic (eg, cefaclor, cephalexin, cefuroxime, cefadroxil). A severe allergic reaction includes a severe rash, hives, breathing difficulties, or dizziness. Ask your health care provider if you are unsure if you are allergic to Penicillin G Benzathine Suspension.

  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

  • Diabetes patients - Penicillin G Benzathine Suspension may cause the results of some tests for urine glucose to be wrong. Ask your doctor before you change your diet or the dose of your diabetes medicine.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Penicillin G Benzathine Suspension. To prevent pregnancy, use an extra form of birth control (eg, condoms).

  • Use Penicillin G Benzathine Suspension with caution in the ELDERLY; they may be more sensitive to its effects.

  • Use Penicillin G Benzathine Suspension with caution in NEWBORNS; they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Penicillin G Benzathine Suspension while you are pregnant. Penicillin G Benzathine Suspension is found in breast milk. If you are or will be breast-feeding while you use Penicillin G Benzathine Suspension, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Penicillin G Benzathine Suspension:


All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Pain, swelling, or bleeding at the injection site; mild diarrhea; worsening of arthritis.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; blood in urine; bloody stools; chest pain; chills; extreme tiredness; fainting; fast heartbeat; fever; flushing with lightheadedness or fainting; hallucinations; headache; itching; muscle pain; nausea; pounding in the chest; rapid breathing; seizures; severe diarrhea; stomach pain/cramps; vaginal irritation or itching; vomiting; worsening of skin lesions.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Penicillin G Benzathine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms of may include diarrhea; nausea; vomiting.


Proper storage of Penicillin G Benzathine Suspension:

Store Penicillin G Benzathine Suspension in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Dispose of properly after use. Keep Penicillin G Benzathine Suspension, as well as needles, syringes, or other materials, out of the reach of children and away from pets.


General information:


  • If you have any questions about Penicillin G Benzathine Suspension, please talk with your doctor, pharmacist, or other health care provider.

  • Penicillin G Benzathine Suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Penicillin G Benzathine Suspension. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Penicillin G Benzathine resources


  • Penicillin G Benzathine Side Effects (in more detail)
  • Penicillin G Benzathine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Penicillin G Benzathine Drug Interactions
  • Penicillin G Benzathine Support Group
  • 11 Reviews for Penicillin G Benzathine - Add your own review/rating


Compare Penicillin G Benzathine with other medications


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  • Cutaneous Bacillus anthracis
  • Deep Neck Infection
  • Diphtheria
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  • Lyme Disease, Arthritis
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  • Lyme Disease, Neurologic
  • Meningitis
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  • Meningitis, Pneumococcal
  • Neurosyphilis
  • Otitis Media
  • Pneumonia
  • Prevention of Perinatal Group B Streptococcal Disease
  • Rat-bite Fever
  • Rheumatic Fever Prophylaxis
  • Skin Infection
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  • Syphilis, Latent
  • Tertiary Syphilis
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  • Upper Respiratory Tract Infection

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